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Cushing’s disease overview brochure

Cushing’s disease overview brochure

This brochure provides education for people who want to know more about Cushing’s disease.

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FAQs

FAQs

Find answers to frequently asked questions about SIGNIFOR.

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What is SIGNIFOR?

SIGNIFOR is a prescription medicine used to treat Cushing’s disease in adults who cannot have surgery or have failed surgery. It is not known if SIGNIFOR is safe and effective for use in children.

IMPORTANT SAFETY INFORMATION

Before starting SIGNIFOR, tell your doctor about all your medical conditions, including if you:

INDICATION(S) AND IMPORTANT SAFETY INFORMATION

What is SIGNIFOR?

SIGNIFOR is a prescription medicine used to treat Cushing’s disease in adults who cannot have surgery or have failed surgery. It is not known if SIGNIFOR is safe and effective for use in children.

IMPORTANT SAFETY INFORMATION

Before starting SIGNIFOR, tell your doctor about all your medical conditions, including if you:

Tell your healthcare provider about all the medicines you take, including any prescription and over-the-counter medicines, vitamins, or herbal supplements.

SIGNIFOR and other medicines may affect each other, causing side effects. Especially tell your doctor if you take medicines to control your heartbeat (anti-arrhythmics), that can affect the electrical system of your heart (QT prolongation), to control your blood pressure (beta-blockers or calcium channel blockers), to control electrolyte levels in your blood (such as potassium or magnesium), cyclosporine, and/or bromocriptine.

What are the possible side effects of SIGNIFOR?

SIGNIFOR may cause serious side effects including:

The most common side effects of SIGNIFOR include diarrhea, nausea, high blood sugar, headache, abdominal pain, fatigue, diabetes mellitus, injection-site reactions, common cold, hair loss, weakness, fluid retention, and abnormal blood test result for glycosylated hemoglobin.

These are not all the possible side effects of SIGNIFOR. Call your doctor for medical advice about side effects. You are encouraged to report side effects of prescription drugs to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

SIGNIFOR (pasireotide) injection, for subcutaneous use, is available as a 0.3 mg/1 mL, 0.6 mg/1 mL, and 0.9 mg/1 mL pasireotide (as diaspartate) glass ampule.

Please see the accompanying full Prescribing Information, including the Medication Guide.